KIOST Announces First Molecular and Biochemical Characterization of Agarase
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KIOST Announces First Molecular and Biochemical Characterization of Agarase
Partial hydrolysis product of agarase proves to have an effect of containing the decomposition of hyaluronic acid

27(Tue), Sep, 2022




President Kim Woong-seo of KIOST. (Photos: KIOST)


The Korea Institute of Ocean Science and Technology (KIOST) revealed the outcome of recent research which showed that partial hydrolysis of agarase, isolated from a marine microorganism, contains the decomposition of hyaluronic acid, which is effective in moisturizing human skin. 

According to his thesis, Lee Young-duk, a researcher with KIOST¡¯s Jeju Research Center, contributed to the international journal ¡°Marine Drugs,¡± the partial hydrolysis product of agarase was found to have an excellent effect of containing hyaluronic acid, differing from the full hydrolysis product of agaro-oligosaccharides. 

In particular, the research discovered the first efficacy of the partial hydrolysis product of agarase. 
Agarase has so far been utilized simply as a processed food, and the full hydrolysis of agarase has huge costs, standing the way of industrial utilization. 

But the research found that the part hydrolysis of agarase being not gelated can be freely processed as a raw material without restrictions. 

That differs from the generally solidified agarose, on top of a strong point of the stable production of the partial hydrolysis of agarase, even with small amounts of the enzyme. 

In accordance with the late trend of nurturing the marine bio industry as a future growth engine, the following has been galvanized: the development of grain, energy, industrial materials and medicine, utilizing biomaterials, isolated from marine microorganisms. 

Research on the utilization of agaro-oligosaccharide as food, cosmetics and medicines is on the rise, particularly with a focus on raising the efficiency rate of the partial hydrolysis of agarase.





A view on the cultivation of gar-degrading marine bacterium Gilvimarinus agarilyticus JEA5, collected from a seaweed habitat of Jeju¡¯s coastal area.


A research team with the Jeju Marine Research Center under the umbrella of KIOST¡¯s Jeju Research Institute identified Gilvimarinus agarilyticus JEA5, collected from a seaweed habitat of Jeju¡¯s coastal area, isolated the enzyme of decomposing agarase, and secured mass production technology through gene recombination. 

It was transferred to LalaIt¡¯s, an in-house firm of KIOST.

KIOST President Kim Woong-seo said, ¡°As ocean and marine resources have emerged as core driving forces for national growth, the proving of the efficacy of the partial hydrolysis of agarase is hoped to be utilized as functional materials in diverse areas such medicines and cosmetics in the years to come.¡± 

KIOST will endeavor to continue to explore materials from ocean and marine resources and contribute to industrialization, such as mass production and standardization, he said. 




The Korea Institute of Ocean Science and Technology (KIOST) received a certificate on measuring underwater ship radiated noise from the American Bureau of Shipping (ABS)


KIOST Certified by ABS to Measure Underwater Ship Radiated Noise 

The Korea Institute of Ocean Science and Technology (KIOST) became the nation¡¯s first entity to be certified on measuring underwater ship radiated noise from the American Bureau of Shipping (ABS).

In 2021, KIOST obtained a certification on the measuring of underwater ship radiated noise from Det Norske Veritas (DNV). 

It is significant that KIOST become the first Korean institution to be certified by ABS. ABS has been committed to setting standards for safety and excellence as one of the world¡¯s leading ship classification organizations.

Of late, the International Maritime Organization (IMO) is moving to reinforce restrictions on underwater ship radiated noises to reduce the damages of the marine ecology, caused by rising maritime traffic volumes and making ships large. 

Korean and other shipping associations across the world have been developing their own regulations on classifying ships by standardizing the method of measuring and analyzing underwater ship radiated noises to cope with IMO¡¯s restrictions on the noises. 

   
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